Collaborations with ARUP: How to Start and What to Expect
Step 1: Connect with an ARUP facultyWe have over 40 University of Utah faculty members associated with ARUP (majority are faculty from the Dept of Pathology, but we also have faculty from the Dept of Pediatrics). In order to discuss your project in a meaningful way, the first step will be to get connected with an ARUP faculty who has common academic diagnostic interests with you. Click here to identify an ARUP faculty.
Step 2: Discuss the project, & present a technical seminar at ARUPThis can be coordinated by your ARUP faculty contact, or by Karen McRae ( karen.mcrae [at] aruplab.com; 801-583-2787 x3615). You will get feedback from a broader audience within ARUP as to how your work may fit with ARUP, and a sense of what work remains for the technology (or the biomaker as case may be) to be used in a the diagnostic laboratory setting.
Step 3: Joint studiesIf there is a fit between your work and ARUP, we may move on to designing a collaborative
study with you.
The study may include:
- A clinical study to validate the analytical and/or medical performance of a test method, biomarker, or algorithm.
- A proof-of-principle study of a device or method.
- Design and validate an assay that could be implemented as a test at ARUP, as well as possibly at other diagnositc laboratories.
If through the collaboration we are able to create a test or a process with good analytical performance, or if we are able to collect enough evidence of medical utility or good cost benefit to heathcare, then the ARUP faculty will sponsor the technology, and work on implementing it at ARUP (see example of a recent successful University of Utah ARUP collaboration click here). If your work is patentable, we work closely with our university's Technology Commercialization Office (TCO) so that appropriate protection and licensing arrangements can be put in place.
ARUP Resources Available for Collaborative Projects
There are many possibilities for ARUP to be a resource to U faculty seeking potential application of their work in human diagnostics. Some are included in the following:
- Clinical assay development expertise (>60 scientists; over 600 published articles on clinical assays)
- Large specimen collection (blood, urine, tissue with test data) available to ARUP faculty and their collaborators
- Market experience (evaluation of medical utility, market evaluation, and IP review)
- Industry networks - ARUP has ongoing projects and relationships with leading consortiums and companies in the diagnostic industry
- Client network - ARUP serves over 3,200 hospitals in 50 U.S. states. ARUP has a program to help these hospitals implement new tests and new technologies
- Our pathology faculty have expertise in:
- Anatomic pathology
Clinical pathology
Bioinformatics
Biostatistics
Disease databases
High resolution DNA melting
High throughput gene sequencing
Integrated test results reporting
Laboratory robotics & automation
Luminex multiplexing assays
Mass spectrometry
Newborn screening
Proteomics
Real-time PCR
Translational research