ARUP Online Scientific Resource

The Advanced Technology Group at ARUP has the world’s leading expertise in advanced nucleic acid analysis methods. Dr. Carl Wittwer is the inventor of the LightCycler real-time PCR techniques and high-resolution melting analysis, which are used widely in molecular pathology today. Dr. Voelkerding has an active interest in next generation sequencing.

Cardiac risk assessment and reduction.
Lipid markers, hypertension, thrombotic risk, therapeutic monitoring, congestive heart failure, coronary event markers.

Interfaces for clinical studies

Fluorescent in situ hybridization (FISH)
Karyotyping
Comparative genomic hybridization (CGH)
Copy number variants (CNV)

ARUP maintains a premier core facility.

Hormone assays, thyroid cancer, vitamin deficiencies

General flow cytometry, immunology
Hematopoietic flow cytometry (blood and bone marrow)

Neonatal and pediatric development disorders
Inherited disorders of metabolism, newborn screening
Cystic fibrosis
Hearing loss

Leukemia and lymphomas
Coagulation disorders
Thalasemias

 

Cytokines
Autoimmunity
Immunodeficiency
Bacterial pathogenesis
Infectious Serology

Molecular diagnosis for viruses, bacteria, and fungi

ARUP has an onsite machining and fabrication shop for custom applications.

Colorectal cancer
Hepatocellular carcinoma
Inflammatory bowel disease

 

Meta Analysis
Clinical information systems
Mathematical modeling

Salivary tumor

Under the guidance of Dr Peter Jensen, ARUP has formed a Translational Research Group whose primary focus is on the use of proteomic technologies to bridge the gap between marker discovery and implementable diagnostic tests.

Assembles reagents and plates for high-throughput tests.
Coating of microtiter plates cDNA production standards.

ELISA
Luminex immunochemistry
Electrophoresis

Therapeutic drug monitoring
Companion diagnostics
Drugs of abuse

Solid tumors
  Anatomic pathology
  Clinical pathology
  Specialty areas in lung, breast, prostates, liver and colon cancers