Disease and Technology Expertise

The University of Utah Department of Pathology and ARUP Laboratories house experts in many areas of clinical and anatomic pathology, as well as laboratory medicine. See complete listing here...

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Expertise

Advanced Molecular Pathology Techniques

The Advanced Technology Group at ARUP focuses on emerging nucleic acid analysis methods for diagnostics. Dr. Carl Wittwer is the inventor of the LightCycler real-time PCR techniques and high-resolution melting analysis, which are used widely in molecular pathology today. Dr. Voelkerding has an active interest in next generation sequencing.

Anatomic Pathology

Expertise in areas of anatomic pathology including diagnostic, exfoliative and cytology - providing a full range of consultative and diagnostic services.

Biomedical Informatics

Gene variant annotation and mutation prediction
Disease biomarkers and pathway analysis
HLA and Immuno-informatics MS/MS search alogorithms
Next generation sequencing and data analysis
Test order pattern algorithms and e-marketing

Cardiology

Cardiac risk assessment and reduction
Lipid markers, hypertension, thrombotic risk
Therapeutic monitoring
Congestive heart failure and coronary event markers

Clinical Research Services

Interface for academic clinical research studies.

Cytology

In-house expertise in many areas of cytopathology.

Cytogenetics

Fluorescent in situ hybridization (FISH)
Karyotyping
Cytogenetic microarray techniques

Digital Imaging & Analysis

Expertise in digital slide imaging, software analysis and algorithms for anatomic pathology interpretation.

DNA Sequencing

ARUP maintains a premier core facility, including both traditional Sanger sequencing and next generation sequencing platforms.

Endocrinology

Hormone assays
Thyroid cancer
Vitamin deficiencies

Flow Cytometry

General flow cytometry
Hematopoietic flow cytometry (blood and bone marrow)
Immunology

Genetics Disorders

Neonatal and pediatric developmental disorders
Inherited disorders of metabolism, newborn screening
Biochemical genetics
Cystic fibrosis
Hearing loss
Hemoglobinopathies
X-linked mental retardation

Hematopathology

Immunohistochemistry & Imaging

ARUP maintains state of the art facilities in sample prep automation, immunostaining (Dr. Perkins) and image analysis (Dr. Salama).

Immunology

Autoimmune diseases
Bacterial pathogenesis
Cytokines
Immunodeficiency
Infectious Serology

Infectious Disease

Laboratory Automation

ARUP is a long-time national leader in laboratory efficiency such as track automation and sample storage/retrieval.

Liver and GI

Colorectal cancer
Hepatocellular carcinoma
Inflammatory bowel disease

Mass Spectometry

ARUP maintains state of the art mass spectrometry facilities - in both production testing and research efforts.

Oral & Maxillofacial Pathology

Oral and salivary tumors.

PharmaDx Initiative

Interface for pharmaceutical partners: clinical trials, development of companion diagnostics, therapeutic drug monitoring, and other drug-related testing.

Proteomics

Established expertise in proteomic technologies and data analysis to bridge the gap between disease marker discovery and diagnostic testing.

Reagent Lab

Assembles reagents and plates for high-throughput testing platforms
cDNA production standards
Custom coating of microtiter plates
High quality in-house reagent production

Renal Pathology

Special focus area of renal pathways and pathogenesis.

Special Chemistry

Vitamins, biogenic amines (tumor markers), porphyrins and calculi
Chromatography and spectrophotometry
Electrophoresis, ELISA, Luminex immunochemistry

Toxicology & Pharmacogenetics

Companion diagnostics
Drugs of abuse
Pain management
Therapeutic drug monitoring

Tumors

Anatomic pathology, clinical pathology and surgical pathology.
Special focus areas in lung, breast, prostate, liver and colon cancers.