Disease and Technology Expertise
The University of Utah Department of Pathology and ARUP Laboratories house experts in many areas of clinical and anatomic pathology, as well as laboratory medicine. See complete listing here...
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The Advanced Technology Group at ARUP focuses on emerging nucleic acid analysis methods for diagnostics. Dr. Carl Wittwer is the inventor of the LightCycler real-time PCR techniques and high-resolution melting analysis, which are used widely in molecular pathology today. Dr. Voelkerding has an active interest in next generation sequencing.
Expertise in areas of anatomic pathology including diagnostic, exfoliative and cytology - providing a full range of consultative and diagnostic services.
Gene variant annotation and mutation prediction
Disease biomarkers and pathway analysis
HLA and Immuno-informatics MS/MS search alogorithms
Next generation sequencing and data analysis
Test order pattern algorithms and e-marketing
Cardiac risk assessment and reduction
Lipid markers, hypertension, thrombotic risk
Congestive heart failure and coronary event markers
In-house expertise in many areas of cytopathology.
Fluorescent in situ hybridization (FISH)
Cytogenetic microarray techniques
Expertise in digital slide imaging, software analysis and algorithms for anatomic pathology interpretation.
ARUP maintains a premier core facility, including both traditional Sanger sequencing and next generation sequencing platforms.
General flow cytometry
Hematopoietic flow cytometry (blood and bone marrow)
Neonatal and pediatric developmental disorders
Inherited disorders of metabolism, newborn screening
X-linked mental retardation
Leukemia and lymphomas
ARUP maintains state of the art facilities in sample prep automation, immunostaining (Dr. Perkins) and image analysis (Dr. Salama).
Molecular diagnosis for viruses, bacteria, and fungi.
ARUP is a long-time national leader in laboratory efficiency such as track automation and sample storage/retrieval.
Inflammatory bowel disease
ARUP maintains state of the art mass spectrometry facilities - in both production testing and research efforts.
Oral and salivary tumors.
Interface for pharmaceutical partners: clinical trials, development of companion diagnostics, therapeutic drug monitoring, and other drug-related testing.
Established expertise in proteomic technologies and data analysis to bridge the gap between disease marker discovery and diagnostic testing.
Assembles reagents and plates for high-throughput testing platforms
cDNA production standards
Custom coating of microtiter plates
High quality in-house reagent production
Vitamins, biogenic amines (tumor markers), porphyrins and calculi
Chromatography and spectrophotometry
Electrophoresis, ELISA, Luminex immunochemistry
Drugs of abuse
Therapeutic drug monitoring