Updates in Mastocytosis


In “Updates in Mastocytosis,” Dr. Tracy George discusses the diagnosis, classification, and recent clinical trials work in mast cell disease. This orphan disease has been of intense interest recently with breakthrough therapies based on targeting of the D816V KIT mutation, approved by the FDA and EMA. Dr. George is an international expert in the pathology of mast cell diseases and a founding member of AIM (American Initiatives in Mast Cell Diseases). The inaugural meeting of AIM will occur at Stanford University in May 2019.

Originally published on March 12, 2019

Lecture Presenter

Tracy I. George, MD

Tracy I. George, MD

Professor of Pathology
University of Utah School of Medicine
Executive Director, Clinical Trials and PharmaDx
ARUP Laboratories
Medical Director, Hematopathology
ARUP Laboratories

Dr. George is a professor of pathology at the University of Utah School of Medicine. She completed her MD and residency training in anatomic pathology and laboratory medicine at the University of California San Francisco, with fellowships in hematopathology and surgical pathology at Stanford University. Dr. George is board certified in anatomic pathology, clinical pathology, and hematology by the American Board of Pathology. Her research interests include mast cell disease and laboratory hematology. Dr. George has authored more than 100 publications, is Vice President of Scientific Communications for the International Society for Laboratory Hematology, and Co-Editor-in-Chief of the International Journal of Laboratory Hematology. She received the College of American Pathologists Lifetime Achievement Award in 2014.


After this presentation, participants will be able to:

  • Recognize the characteristics of neoplastic mast cells in bone marrow aspirate smears and bone marrow core biopsies
  • Classify subtypes of systemic mastocytosis in the bone marrow
  • Apply a diagnostic algorithm for patients with suspected systemic mastocytosis

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories