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Diagnosis of Monoclonal Gammopathies
Monoclonal gammopathies are diagnosed by a triad of criteria including clinical symptoms of the disease, bone marrow analysis and clinical laboratory testing. Protein electrophoresis and immunofixation in serum and urine are the most common tests in clinical laboratory for diagnosis of monoclonal gammopathies. More recently, serum free light chain testing has become an important tool for diagnosis and prognosis of these conditions. The indications and limitation of these clinical laboratory tests are reviewed in this presentation.
Originally presented January 24th, 2011 in Salt Lake City, Utah.
Julio Delgado, MD, MS
Assistant Professor of Pathology, University of Utah School of Medicine
Medical Director, Immunology, ARUP Laboratories
Associate Director H&I Laboratory, University of Utah Health Care
Dr. Delgado is an Assistant Professor of Pathology at the University of Utah School of Medicine. He received his M.D. from Universidad Industrial de Santander in Colombia, clinical residency training in Clinical Pathology and research fellowship in Immunology from Harvard Medical School. He received his M.S. degree in Epidemiology from Harvard School of Public Health.
Dr. Delgado is board certified in Clinical Pathology and Histocompatibility laboratory testing by the American Board of Pathology and the American Board of Histocompatibility and Immunogenetics.
After this presentation, attendees will be able to:
- Review clinical laboratory tests available for diagnosis of monoclonal gammopathies.
- Review clinical presentation and diagnostic criteria of most common monoclonal gammopathies.
University of Utah School of Medicine and ARUP Laboratories