Multiple Sclerosis: Clinical Features & Laboratory Evaluation


Multiple sclerosis (MS) is a common neurologic disorder and one of the most common CNS causes of disability in young adults. It is a chronic, immune-mediated demyelinating disorder affecting neurons of the central nervous system. Symptoms are often nonspecific, and patients’ clinical courses can vary widely. This presentation provides an overview of the pathophysiology and risk factors for MS, the clinical, radiologic, and laboratory diagnostic processes, and the management of patients with MS.

Originally published on October 10, 2018

Lecture Presenter

Nicole E. Stanley, MD

Nicole E. Stanley, MD

PGY 3, Anatomic and Clinical Pathology Resident
University of Utah School of Medicine

Dr. Nicole Stanley received her Bachelor’s Degree in History from the University of Nebraska at Lincoln and then another Bachelor’s Degree in Nutrition Science from Oregon State. Nicole took a year out of her medical school curriculum at Oregon Health & Science University to complete a Post-Sophomore Pathology Fellowship. She is currently a third-year pathology resident at the University of Utah School of Medicine.


After this presentation, participants will be able to:

  • Discuss the epidemiology, etiology, pathophysiology, and risk factors for Multiple Sclerosis (MS)
  • Describe the clinical manifestations, differential diagnosis, and clinical and laboratory evaluation of MS
  • Describe the clinical course, management, and monitoring of patients with MS

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories