Selected Cases in Nongynecologic Cytopathology: Inflammatory and Infectious Disease

 

Benign infectious and inflammatory mimics of mass lesions clinicoradiologically concerning for malignancy are well known. However, certain less common entities may yield hypocellular material on rapid on-site assessment of small biopsy samples. Additionally, microorganisms or features of infection may be identified on material submitted only for cytologic assessment. This session aims to highlight diagnoses which may be subtle on aspirate or exfoliative cytology and core biopsy material. While more sophisticated molecular methods for identification of microorganisms in paraffin-embedded tissue are now being used, they may not yet be widely available. Therefore, traditional ancillary techniques for histochemical identification of microorganisms will also be reviewed.

Originally published on September 7, 2022

Lecture Presenter

Lesley C. Lomo, MD

Lesley C. Lomo, MD

Associate Professor of Pathology (Clinical)
University of Utah School of Medicine
Medical Director, Anatomic Pathology
ARUP Laboratories

Dr. Lomo is an associate professor of pathology at the University of Utah School of Medicine. She received her medical degree from Wayne State University School of Medicine in Detroit and completed her residency in anatomic and clinical pathology, as well as fellowships in women’s and perinatal pathology, breast pathology, and cytopathology at Brigham and Women’s Hospital in Boston. Dr. Lomo is board certified in anatomic and clinical pathology and cytopathology. She is a member of several professional organizations, including the United States and Canadian Academy of Pathology, the American Society for Clinical Pathology, and the International Society of Gynecological Pathologists. Her research interests include education techniques for pathology trainees and medical students, neoplastic and nonneoplastic endometrial pathology, and biomarkers of malignancy risk in preneoplastic epithelial breast disease.

Objectives

After this presentation, participants will be able to:

  • Using a case-based approach, review selected infectious and inflammatory/nonneoplastic conditions that may radiologically mimic malignant lesions
  • Discuss some of the diagnostic challenges to rapid on-site assessment via aspiration or touch imprint cytology for these lesions
  • Review traditional ancillary techniques that may assist in the diagnosis of these entities in cytologic and small biopsy samples

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories