ARCHIVED: NOT AVAILABLE FOR CREDIT
Harmful Effects of Stored RBC Transfusion:
Bench to Bedside
The goal of transfusion medicine is to manipulate the composition of blood with complete control and without adverse consequences. Dr. Steven Spitalnik presents studies performed in his laboratory at Columbia University concerning the effects of storage on Red Blood Cells (RBCs). His findings on the effects that the aging of cells may have on the recipient of the transfusion include possible complications that can arise both in mouse models as well as human subjects.
Originally presented March 18, 2011 in Salt Lake City, Utah.
Steven Spitalnik, MD
Professor of Pathology and Cell Biology
Columbia University Medical Center
Dr. Spitalnik received his MD from the University of Chicago and has been a tenured Professor and Vice-Chairman of Laboratory Medicine, Department of Pathology, College of Physicians and Surgeons of Columbia University since 2003, and has received numerous teaching awards. He is an active member of many professional organizations, the author of over one hundred peer reviewed articles, and a member of numerous editorial boards, including Analytical Biochemistry, International Journal of Clinical and Experimental Pathology, Transfusion and Journal of Blood Disorders & Transfusion.
After this presentation, attendees will be able to:
- Describe the consequences of red cell clearance
- Discuss the importance of iron status and how it is affected by red cell clearance
- Describe the inflammatory response of RBC transfusions
University of Utah School of Medicine and ARUP Laboratories