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Celiac disease (CD) is a common condition affecting up to 1% of the U.S. population. It is an inflammatory disease of the gastrointestinal tract that occurs in predisposed individuals after gluten ingestion. There are numerous diagnostic modalities that have been implemented over the past several years to aid the diagnosis of CD. They include serologic tests for various antibodies, HLA testing, and gastrointestinal tract biopsies. This presentation is a general overview of CD that includes detailed explanation of CD’s pathophysiology, symptoms, diagnostic modalities, and treatment.
Originally presented October 15, 2012 in Salt Lake City, Utah.
Jolanta Jedrzkiewicz, MD
Resident of Pathology, University of Utah School of Medicine
Dr. Jedrzkiewicz was born and raised in Zywiec, in Southern Poland. She obtained her Bachelor's degree in Molecular and Cell Biology from the University of Connecticut in the U.S. and her M.D. from Poznan University of Medical Sciences in Poland. Currently she is a 2nd year resident in Anatomic and Clinical Pathology with special interests in medical illustration and diseases of the gastrointestinal tract.
After this presentation, participants will be able to:
- List the symptoms of celiac disease.
- Identify the agent that causes celiac disease.
- List criteria for diagnosis.
- Compare and contrast different tests that are used.
- Justify utilization of serology (antibody test).
- List the antibodies that we test for.
- Justify utilization of HLA testing.
- List the HLA tests that are used in assessing the risk.
- Describe current guidelines and recommendations.
University of Utah School of Medicine and ARUP Laboratories