Liquid-Based Pap Test on 36-Year-Old Non-Gravid Woman
by Marianna Sandomirsky, MD, Resident, Saint Louis University School of Medicine
Editor: Brian T. Collins, MD, Professor of Pathology, University of Utah, and Medical Director, Cytopathology, ARUP Laboratories
The patient is 36-year-old, non-gravid woman, day 10 menstrual cycle, on hormone therapy (not otherwise specified). No previous cervical smear sample is available for comparison.
Liquid-based Pap test shows the following:
- Several intermediate-sized groups of crowded columnar cells are present.(Fig. 1).
- Some of groups are arranged in strips and small rosettes and show "feathered" edges.(Fig. 2).
- The nuclei are hyperchromatic with open chromatin and irregular contours.(Fig. 3).
- Most of the cells have single inconspicuous small nucleoli but larger single and multiple eosinophilic nucleoli are also identified. (Fig. 4).
- Scattered markedly enlarged pleomorphic cells and rare single atypical mitotic figures are seen. (Fig. 5).
- The cytoplasm is scant and shows fine vacuolization.
- The background is composed of mild acute inflammation without tumor diathesis or abundant blood.
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