MEN2 Links and Literature
The web links shown below are existing online resources for MEN2 and the RET proto-oncogene. Links to several review journal articles are given, as well as genome and protein links.
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Databases
- Cosmic Database: RET somatic mutations in cancer
- The Human Gene Mutation Database (HGMD®)or Uniprot: For Hirschsprung RET mutations
Genome and protein sequences
- RET gene: NC_000010.9
- RET mRNA: NM_020630.4
- RET protein: HPRD and Uniprot
Literature Reviews
- Kouvaraki, et al. RET proto-oncogene: A review and update of Genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors. Thyroid 2005. 15(6): 531-544.
- de Groot, et al. RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors. Endocrine Reviews 2006. 27(5): 535-60.
- Hansford and Mulligan. Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis. Journal of Medical Genetics 2000. 37:817-827.
- Eng, et al. The relationship between specific RET mutations and disease phenotype in multiple endocrine neoplasia. JAMA 1996. 276(19): 1575-1579.
- Brandi, et al. Consensus: Guidelines for Diagnosis and Therapy of MEN Type 1 and Type 2. Journal of Clinical Endocrinology & Metabolism 2001. 86 (12): 5658-5671.